Peptides – The Art of Biohacking – Almost all you need to know about Peptides
a Book By Bogdan Dicoias
Table of Contents
- Introduction
- What Are Peptides?
- Top Twenty Peptides for Biohacking
- The Rise of Peptides
- The Health Benefits of Peptides
- Where to Get Peptides
- How to Use Peptides: Reconstitution, Storage, & Administration
- Best Peptide Stacks for Health Goals
- Frequently Asked Questions About Peptide
- Peptides and flavonols
- Conclusion
- Appendix: Additional Resources
- References
- Glossary
- About the Author
- Acknowledgements
Almost All You Need to Know About Peptides
Introduction
Peptides naturally occur as biological molecules composed of two or more amino acids linked by peptide bonds. They play essential roles in the body, similar to amino acids and proteins. Furthermore, peptides act as signaling molecules that communicate with cells to instruct them on various functions, such as tissue repair, hormone production, and the release of anti-inflammatory compounds.
What Are Peptides?
Peptides are short chains of amino acids, typically comprising 2 to 50 amino acids. They are smaller than proteins but play crucial roles in the body. Peptides function as hormones, enzymes, and signaling molecules, influencing various physiological processes.
Top Twenty Peptides for Biohacking
- BPC-157: Known for its regenerative effects on the gut and other tissues, promoting healing and reducing inflammation.
- TB-500: Aids in tissue repair and regeneration, especially beneficial for muscle injuries and joint health.
- IGF-1 LR3: Promotes muscle growth, fat loss, and overall anabolic effects.
- CJC-1295 without DAC: Increases growth hormone secretion, enhancing muscle growth and fat loss.
- Ipamorelin: Stimulates the release of growth hormone, aiding in muscle growth, fat loss, and recovery.
- GHK-Cu: Known for its skin healing, anti-aging, and regenerative properties.
- Epithalon: Promotes longevity and anti-aging by enhancing telomerase activity.
- MOTS-c: Improves metabolic health, enhances fat loss, and promotes longevity.
- Humanin: Provides protective effects against oxidative stress and aging.
- FOXO4-DRI: Promotes cellular senescence and anti-aging by inhibiting the interaction between FOXO4 and p53.
- Semaglutide: Manages type 2 diabetes and promotes weight loss by increasing insulin secretion and slowing gastric emptying.
- AOD-9604: Reduces body fat and treats obesity by stimulating fat breakdown and inhibiting fat formation.
- Tesofensine (NS2330): Promotes weight loss and treats obesity by reducing appetite through increased neurotransmitter levels.
- Thymosin Alpha-1 (Ta1): Enhances immune function and treats chronic infections by promoting T-cell production and modulating the immune response.
- Selank (TP-7): Reduces anxiety and enhances cognition by modulating neurotransmitters like serotonin and dopamine.
- Bremelanotide (PT-141): Treats sexual dysfunction by activating melanocortin receptors to increase sexual desire.
- Gonadorelin (GnRH): Diagnoses and treats reproductive hormonal disorders by stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
- Thyrotropin Releasing Hormone (TRH) / Protirelin: Diagnoses thyroid disorders and supports cognitive function by increasing the production of thyroid-stimulating hormone (TSH) and prolactin.
- Liraglutide: Treats type 2 diabetes and obesity by enhancing insulin secretion and slowing gastric emptying.
- MK-677 (Ibutamoren): Increases muscle mass, improves bone density, and promotes fat loss by stimulating the release of growth hormone and insulin-like growth factor 1 (IGF-1).
The Rise of Peptides
Two significant factors have recently propelled peptides into the health scene:
- Technological Advancements: Enhancements in peptide circulatory half-lives and therapeutic potency, such as attaching peptides to larger molecules for better absorption or manipulating the amino acid chain for stability in the bloodstream.
- Commercialization: Peptides have become more accessible, especially online. However, this ease of access has raised concerns about the safety and purity of peptides available for purchase.
The Health Benefits of Peptides
Peptides offer a wide range of health benefits, including:
- Improved Sleep: Certain peptides can enhance sleep quality and duration.
- Enhanced Brain Health: Peptides can improve cognitive functions and protect against neurodegenerative diseases.
- Boosted Immune Function: Peptides can strengthen the immune system, making the body more resilient to infections.
- Increased Lean Muscle Growth: Peptides can promote muscle growth and improve body composition.
- Anti-Aging and Longevity Effects: Peptides can slow down aging processes and promote longevity.
- Hair Loss Prevention and Regrowth: Certain peptides can prevent hair loss and stimulate hair regrowth.
- Improved Insulin Sensitivity and Metabolic Health: Peptides can enhance insulin sensitivity and metabolic functions.
- Support for Injury Healing and Recovery: Peptides can accelerate the healing process of injuries and enhance recovery.
Where to Get Peptides
Finding a reputable, high-quality source for peptides can be tricky. Initially, my experience was less than ideal, but through research and consultations with other experts, I learned to discern quality sources. After seeing the astonishing results, I decided to synthesize them myself. These miraculous compounds need to be shared with the entire world. Notably, the head of the United Kingdom’s anti-doping organization stated that 80% of peptides advertised online are adulterated or fake.
For safety and efficacy, the best option is to obtain peptides through a legitimate peptide provider who can develop an appropriate protocol for your needs. You can visit Panacea Biochem for more information.
How to Use Peptides: Reconstitution, Storage, & Administration
Reconstitution
- Clean the Vial: Wipe the vial’s top with an alcohol swab.
- Add Bacteriostatic Water: Use a syringe to add the appropriate amount of bacteriostatic water to the vial.
- Mix Gently: Do not shake the vial. Instead, gently swirl it to mix the peptide.
Storage
- Refrigerate: Store reconstituted peptides in the refrigerator.
- Protect from Light: Keep the vials in a dark place to protect from light.
Administration
- Subcutaneous Injection: Choose an injection site (thighs, abdomen, upper arm, or gluteus medius), pinch the skin, insert the needle at a 45-90 degree angle, inject the peptide, wait five seconds, and then remove the needle.
- Intramuscular Injection: Choose a muscle-rich site (shoulder, thigh, or hip), pinch the skin, insert the needle at a 90-degree angle, inject the peptide, wait five seconds, and then remove the needle carefully.
Best Peptide Stacks for Health Goals
“Recover Like Wolverine” Stack
For joint pain, muscle tears, or enhanced athletic recovery:
- BPC-157: Take 250-350mcg twice daily, or 500-700mcg once daily.
- TB-500: Administer 1.5-2.5mg 2-3 times per week.
- Ipamorelin: Use 100-500mcg 1-3 times daily.
- Tesamorelin: Administer 1mg 1-2 times daily for 5 days per week.
- GHK-Cu: Take 5mg once daily for a 5-10 day cycle.
“Lean and Mean” Stack (Muscle Gain & Fat Loss)
For building muscle and burning fat:
- IGF-1 LR3: Take 50-150mcg once daily for a 4-week cycle.
- Ipamorelin: Use 100-500mcg 1-3 times daily for a 12-week cycle.
- CJC 1295 without DAC: Administer 100mcg 1-3 times daily for a 12-week cycle.
- Tesamorelin: Take 1mg 1-2 times daily for 5 days per week.
“Never Get Sick” Immunity Stack
For bolstering the immune system:
- TB-500: Administer 750mcg once daily, cycling for 3 months on and 3 months off.
- Thymalin: Take 5-10mg once daily for 3-10 days, repeating every 6-12 months.
- LL-37: Use 100mcg twice daily for 4-6 weeks.
“Benjamin Button” Anti-Aging & Longevity Stack
To slow aging and promote longevity:
- Epithalon: Administer 5-10mg three times weekly for 3 weeks, cycling once per year.
- Thymalin: Take 5-10mg once daily for 10 days, cycling 1-2 times per year.
- GHK-Cu: Use an injection of 0.2mL of 100mg/mL solution once daily.
- MOTS-c: Administer 10mg once weekly for 10 weeks, cycling once per year.
- Humanin: Use 1-2mg 1-2 times daily for a 2-8 week cycle, once per year.
- FOXO4-DRI: Take 3mg every other day for 6 days, repeating 1-3 times per year.
Frequently Asked Questions About Peptides
Are Peptides Safe?
Yes, peptides are generally considered safe when sourced from reputable providers, used in the correct dose, and administered properly. However, as they are still experimental, proceed with caution and ideally under professional supervision.
Are There Side Effects?
Side effects are rare and usually result from incorrect use or excessive doses. Common side effects include dry mouth, increased hunger, tingling or numbness, water retention, and mild pain at the injection site.
Are Peptides Legal?
Peptides are not FDA-approved but are not illegal. They cannot be sold or advertised for human consumption but can be labeled as research chemicals. Competitive athletes should be aware of specific peptides banned by sports authorities.
Can Athletes Take Peptides?
Some peptides are banned by sports organizations like NCAA, WADA, and USADA. Athletes should check specific regulations before using peptides.
Where Should I Get Peptides?
The best option is through a healthcare provider. If that’s not possible, reputable online sources include Panacea Biochem.
Do Peptides Need to Be Cycled?
Cycling depends on the peptide. Those affecting the growth hormone pathway typically need cycling. Peptides with shorter half-lives may not require cycling.
What’s Better: Oral, Transdermal, or Injectable?
Injectable forms are generally more effective due to better absorption. However, oral or transdermal forms can be effective for targeted issues like gut health or skin care.
Can You Combine More Than One Peptide into a Single Injection?
Some peptides can be combined, while others cannot. It’s best to consult with a healthcare provider or peptide manufacturer for guidance.
Peptides and Flavonols
Combining flavonols and peptides has been explored in several studies, highlighting potential benefits and mechanisms of interaction. For example, some studies have looked into the binding behaviors of flavonols with peptides and proteins, suggesting that these interactions can influence biological activities such as antioxidant properties and enzyme inhibition.
Flavonols like quercetin, kaempferol, and myricetin are known for their strong antioxidant and anti-inflammatory properties, which could theoretically complement the bioactive functions of peptides. For instance, peptides have been shown to possess various therapeutic properties, including antimicrobial and immune-modulating effects, which might be enhanced when combined with flavonols.
While direct studies on combining flavonols with peptides are limited, the existing research suggests promising avenues for synergistic effects. Flavonols can modulate enzyme activities and reduce oxidative stress, potentially enhancing the stability and efficacy of therapeutic peptides.
Conclusion
Peptides represent an exciting frontier in biohacking, offering a range of benefits that can significantly enhance various aspects of health and performance. As the science and understanding of peptide therapy continue to evolve, more people will likely discover their potential and integrate them into their wellness routines. Remember, while peptides can be powerful tools, they should be used responsibly and with proper guidance to ensure safety and efficacy.
Thank you for joining me on this journey into the art of biohacking with peptides. I hope this text has provided you with valuable insights and practical knowledge to make informed decisions about incorporating peptides into your health regimen.
Internal Links
External Links
Appendix: Additional Resources
For those who wish to delve deeper into the world of peptides, here are some additional resources that can provide further information and support:
- International Peptide Society: A network of healthcare providers specializing in peptide therapy.
- Panacea: www.panaceabiochem.com, known for high-quality peptide treatments.
References
- How to Use Growth Hormone Stacks for a Better Body: Everything You Need to Know About IGF-LR3, GHRP, and GHRH Peptide Stacks
- Demystifying Growth Hormone-Releasing Peptides – Everything You Need to Know About GH, Ipamorelin, Tesamorelin & More!
- Peptides Unveiled: The Best Peptide Stacks for Anti-Aging, Growth Hormone, Deep Sleep, Hair Loss, Enhanced Cognition & Much More!
- The Peptides Podcast: Everything You Need to Know About Anti-Aging, Muscle Gain, Fat Loss & Recovery Peptides
Glossary
- Amino Acids: The building blocks of proteins and peptides, essential for various biological functions.
- Peptide Bonds: Chemical bonds that link amino acids together to form peptides.
- Subcutaneous Injection: An injection administered into the layer of skin directly below the dermis and epidermis.
- Intramuscular Injection: An injection administered directly into a muscle.
About the Author
Bogdan Dicoias
Bio Chemist, Principal Investigator, Laboratory Director at Panacea Bio Chem www.panaceabiochem.com, Director at Lust for Redolence www.lustperfumes.com
Bogdan Dicoias is the Laboratory Director at Panacea Bio Chem. With extensive experience in peptide research and application, Bogdan is dedicated to exploring the potential of peptides to revolutionize health and performance. His work focuses on developing safe, effective, and innovative peptide therapies to enhance human well-being.
Acknowledgements
I would like to extend my gratitude to all the researchers, healthcare providers, and biohackers who have contributed to the growing body of knowledge on peptide therapy. Your dedication and pioneering spirit inspire and guide the work presented in this book.
Bogdan Dicoias
Peptides – The Art of Biohacking
By Bogdan Dicoias
Table of Contents
- Introduction
- What Are Peptides?
- The Rise of Peptides
- The Health Benefits of Peptides
- Where to Get Peptides
- How to Use Peptides: Reconstitution, Storage, & Administration
- Best Peptide Stacks for Health Goals
- Frequently Asked Questions About Peptides
- Conclusion
- Appendix: Additional Resources
- References
- Glossary
- About the Author
- Acknowledgements
Introduction
I receive questions about peptides nearly every day, such as:
- What exactly are peptides?
- How do they work in the body?
- What are the best sources?
- How do you administer them?
- How can peptides be stacked for optimal effects?
- Are they safe?
- Are they legal?
I understand why these questions persist. Peptide therapy is relatively new to the general population, with few experts discussing it, although that is changing. Additionally, peptides aren’t FDA approved or patentable, so despite their daily use by some of the smartest functional medicine physicians, most mainstream health websites avoid the topic. Consequently, people must seek alternative sources for information on peptides.
My aim is to educate and be a reliable source of information on the fascinating field of peptide therapy. Not only have I personally experienced their benefits, but I also believe peptides have the potential to revolutionize human performance, athletic recovery, anti-aging, immune treatments, skin and hair restoration, and more.
What Are Peptides?
Peptides are naturally occurring biological molecules composed of two or more amino acids linked by peptide bonds. Like amino acids and proteins, peptides play essential roles in the body, serving as signaling molecules that communicate with cells to instruct them on various functions, such as tissue repair, hormone production, or the release of anti-inflammatory compounds.
Structurally, peptides relate to amino acids and proteins as follows:
- Amino acids are individual molecules.
- Peptides are generally short chains of 2-50 amino acids.
- Proteins are long chains of 50+ amino acids.
Despite their relatively recent spotlight, peptides have been used therapeutically in medicine for over a century. Life-saving medicines like morphine, penicillin, and insulin are peptides, and there are many peptide-based vaccines.
The Rise of Peptides
Two significant factors have recently propelled peptides into the health scene:
- Technological advancements: Enhancements in peptide circulatory half-lives and therapeutic potency, such as attaching peptides to larger molecules for better absorption or manipulating the amino acid chain for stability in the bloodstream.
- Commercialization: Peptides have become more accessible, especially online. However, this ease of access has raised concerns about the safety and purity of peptides available for purchase, a topic I will discuss further below.
The Health Benefits of Peptides
Why would someone go through the trouble and expense of sourcing and using peptides? Simply put, the results can be remarkable. Personally, I’ve used BPC-157 to alleviate gut inflammation and heal various injuries, such as golfer’s elbow and a torn hamstring. LL-37 helped my gut recover from giardia, and Semax provided a nootropic boost without affecting sleep or causing anxiety.
When administered correctly, peptides replenish natural levels that decline with age, offering benefits such as:
- Improved sleep
- Enhanced brain health
- Boosted immune function
- Increased lean muscle growth
- Anti-aging and longevity effects
- Hair loss prevention and regrowth
- Improved insulin sensitivity and metabolic health
- Support for injury healing and recovery
Peptides can have such broad effects because they act as circulating hormones, neurotransmitters, and local regulators, playing a fundamental role in human development, reproduction, physiology, and behavior. Their high specificity and ability to penetrate cell membranes make them effective and low in toxicity due to their short half-lives, which prevent accumulation in organs like the liver or kidneys.
Where to Get Peptides
Peptides are not patentable, which means pharmaceutical companies can’t profit from them, so they won’t be marketed through conventional healthcare channels. Though safe and effective, peptides are not FDA-approved and are largely unregulated. They cannot be legally sold or advertised for human consumption, a reason why you’ll see them labeled as such on websites.
Finding a reputable, high-quality source for peptides can be tricky. Initially, my experience was less than ideal, but through research and consultations with experts, I learned to discern quality sources. Notably, the head of Switzerland’s anti-doping organization stated that 80% of peptides advertised online are adulterated or fake.
For safety and efficacy, the best option is to obtain peptides through a legitimate healthcare provider who can develop an appropriate protocol for your needs. You can visit www.panaceabiochem.com for more information.
How to Use Peptides: Reconstitution, Storage, & Administration
There are various methods to administer peptides, depending on the peptide and desired benefits. Some can be applied topically, taken orally, used intranasally, or injected.
For example:
- Topical application: Best for skin benefits or injury repair (e.g., Panacea Patch™).
- Oral administration: Convenient for gut health benefits (e.g., Panacea Capsule™), though few peptides are stable enough for this route.
- Intranasal application: Effective for targeting the brain (e.g., Panacea Nostril™).
- Injection: The most effective and common method, albeit more complex (e.g., Panacea EZnject™).
Injection Instructions
Subcutaneous Injection:
- Choose an injection site (thighs, abdomen, upper arm, or buttocks).
- Pinch the skin and insert the needle at a 45-90 degree angle.
- Inject the peptide, wait five seconds, and then remove the needle.
Intramuscular Injection:
- Choose a muscle-rich site (shoulder, thigh, or hip).
- Pinch the skin and insert the needle at a 90-degree angle.
- Inject the peptide and remove the needle carefully.
Post-Injection Tips
For both injection types, massaging the area for 30-60 seconds post-injection helps absorption. Dispose of needles responsibly in a sharps disposal bin.
Best Peptide Stacks for Health Goals
“Recover Like Wolverine” Stack
For joint pain, muscle tears, or enhanced athletic recovery:
- BPC-157: 250-350mcg 2x/day, or 500-700mcg 1x/day.
- TB-500: 1.5-2.5mg 2-3x/week.
- Ipamorelin: 100-500mcg 1-3x/day.
- Tesamorelin: 1mg 1-2x/day for 5 days per week.
- GHK-Cu: 5mg 1x/day for a 5-10 day cycle.
“Lean and Mean” Stack (Muscle Gain & Fat Loss)
For building muscle and burning fat:
- IGF-1 LR3: 50-150mcg 1x/day for a 4-week cycle.
- Ipamorelin: 100-500mcg 1-3x/day for a 12-week cycle.
- CJC 1295 without DAC: 100mcg 1-3x/day for a 12-week cycle.
- Tesamorelin: 1mg 1-2x/day for 5 days per week.
“Never Get Sick” Immunity Stack
For bolstering the immune system:
- TB-500: 750mcg 1x/day, cycle for 3 months on/3 months off.
- Thymalin: 5-10mg 1x/day for 3-10 days, repeat every 6-12 months.
- LL-37: 100mcg 2x/day for 4-6 weeks.
“Benjamin Button” Anti-Aging & Longevity Stack
To slow aging and promote longevity:
- Epithalon: 5-10mg 3x/week for 3 weeks, cycle 1x/year.
- Thymalin: 5-10mg 1x/day for 10 days, cycle 1-2x/year.
- GHK-Cu: Injection: 0.2mL of 100mg/mL, 1x/day.
- MOTS-c: 10mg 1x/week for 10 weeks, 1x/year.
- Humanin: 1-2mg 1-2x/day for a 2-8 week cycle, 1x/year.
- FOXO4-DRI: 3mg every other day for 6 days, repeat 1-3x/year.
Frequently Asked Questions About Peptides
Are Peptides Safe?
Yes, peptides are generally considered safe when sourced from reputable providers, used in the correct dose, and administered properly. However, as they are still experimental, proceed with caution and ideally under professional supervision.
Are There Side Effects?
Side effects are rare and usually result from incorrect use or excessive doses. Common side effects include dry mouth, increased hunger, tingling or numbness, water retention, and mild pain at the injection site.
Are Peptides Legal?
Peptides are not FDA-approved but are not illegal. They cannot be sold or advertised for human consumption but can be labeled as research chemicals. Competitive athletes should be aware of specific peptides banned by sports authorities.
Can Athletes Take Peptides?
Some peptides are banned by sports organizations like NCAA, WADA, and USADA. Athletes should check specific regulations before using peptides.
Where Should I Get Peptides?
The best option is through a healthcare provider. If that’s not possible, reputable online sources include CanLab Research and Peptide Sciences.
Do Peptides Need to Be Cycled?
Cycling depends on the peptide. Those affecting the growth hormone pathway typically need cycling. Peptides with shorter half-lives may not require cycling.
What’s Better: Oral, Transdermal, or Injectable?
Injectable forms are generally more effective due to better absorption. However, oral or transdermal forms can be effective for targeted issues like gut health or skin care.
Can You Combine More Than One Peptide into a Single Injection?
Some peptides can be combined, while others cannot. It’s best to consult with a healthcare provider or peptide manufacturer for guidance.
Conclusion
Peptides represent an exciting frontier in biohacking, offering a range of benefits that can significantly enhance various aspects of health and performance. As the science and understanding of peptide therapy continue to evolve, more people will likely discover their potential and integrate them into their wellness routines. Remember, while peptides can be powerful tools, they should be used responsibly and with proper guidance to ensure safety and efficacy.
Thank you for joining me on this journey into the art of biohacking with peptides. I hope this book has provided you with valuable insights and practical knowledge to make informed decisions about incorporating peptides into your health regimen.
Appendix: Additional Resources
For those who wish to delve deeper into the world of peptides, here are some additional resources that can provide further information and support:
- International Peptide Society: A network of healthcare providers specializing in peptide therapy.
- Panacea Bio Chem: A laboratory which offers the purest peptides from United Kingdom
References
- How to Use Growth Hormone Stacks for a Better Body: Everything You Need to Know About IGF-LR3, GHRP, and GHRH Peptide Stacks
- Demystifying Growth Hormone-Releasing Peptides – Everything You Need to Know About GH, Ipamorelin, Tesamorelin & More!
- Peptides Unveiled: The Best Peptide Stacks for Anti-Aging, Growth Hormone, Deep Sleep, Hair Loss, Enhanced Cognition & Much More!
- The Peptides Podcast: Everything You Need to Know About Anti-Aging, Muscle Gain, Fat Loss & Recovery Peptides
Glossary
- Amino Acids: The building blocks of proteins and peptides, essential for various biological functions.
- Peptide Bonds: Chemical bonds that link amino acids together to form peptides.
- Subcutaneous Injection: An injection administered into the layer of skin directly below the dermis and epidermis.
- Intramuscular Injection: An injection administered directly into a muscle.
- Growth Hormone (GH): A hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals.
- Insulin-Like Growth Factor 1 (IGF-1): A hormone similar in structure to insulin, plays an important role in childhood growth and anabolic effects in adults.
- BPC-157: A peptide known for its regenerative effects on the gut and other tissues.
- LL-37: An antimicrobial peptide that helps modulate the immune response and heal infections.
About the Author
Bogdan Dicoias
Bio Chemist, Principal Investigator, Laboratory Director at Panacea Bio Chem
Bogdan Dicoias is a biochemist and the Laboratory Director at Panacea Bio Chem. With extensive experience in peptide research and application, Bogdan is dedicated to exploring the potential of peptides to revolutionize health and performance. His work focuses on developing safe, effective, and innovative peptide therapies to enhance human well-being. Amongst peptide synthesys he is creating the unique formula perfumes with pinocembrin, being the owner of www.lustperfumes.com
Acknowledgements
I would like to extend my gratitude to all the researchers, healthcare providers, and biohackers who have contributed to the growing body of knowledge on peptide therapy. Your dedication and pioneering spirit inspire and guide the work presented in this book.
Knowledge is power
Delve into this A MUST READ: Allmost all you need to know about peptides before experimenting (watch the video on this page with Dr. Edwin Lee)

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